<SEC-DOCUMENT>0000814133-14-000049.txt : 20140624
<SEC-HEADER>0000814133-14-000049.hdr.sgml : 20140624
<ACCEPTANCE-DATETIME>20140610131220
ACCESSION NUMBER:		0000814133-14-000049
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20140610
DATE AS OF CHANGE:		20140610

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CEMPRA, INC.
		CENTRAL INDEX KEY:			0001461993
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				262644445
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-86624
		FILM NUMBER:		14901477

	BUSINESS ADDRESS:	
		STREET 1:		6320 QUADRANGLE DRIVE
		STREET 2:		SUITE 100
		CITY:			CHAPEL HILL
		STATE:			NC
		ZIP:			27517-8149
		BUSINESS PHONE:		919-313-6617

	MAIL ADDRESS:	
		STREET 1:		6320 QUADRANGLE DRIVE
		STREET 2:		SUITE 100
		CITY:			CHAPEL HILL
		STATE:			NC
		ZIP:			27517-8149

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cempra Holdings, LLC
		DATE OF NAME CHANGE:	20090414

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			WASATCH ADVISORS INC
		CENTRAL INDEX KEY:			0000814133
		IRS NUMBER:				870319391
		STATE OF INCORPORATION:			UT
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		505 WAKARA WAY
		STREET 2:		3RD FLOOR
		CITY:			SALT LAKE CITY
		STATE:			UT
		ZIP:			84108
		BUSINESS PHONE:		8015330777

	MAIL ADDRESS:	
		STREET 1:		505 WAKARA WAY
		STREET 2:		3RD FLOOR
		CITY:			SALT LAKE CITY
		STATE:			UT
		ZIP:			84108
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>cemp614.txt
<TEXT>
SCHEDULE 13G
Amendment No. 3
Name of Issuer: Cempra Inc
Title of Class of Securities: Common Stock
CUSIP Number: 15130J109
Item 1: Reporting Person: Wasatch Advisors, Inc. 87-0319391
Item 2: Check Box If Member of Group: Not Applicable
Item 3: SEC Use
Item 4: Place of Organization: Utah
Items 5-8: Number of Shares Owned With:
Item 5: Sole Voting Power: 3,454,456
Item 6: Shared Voting Power: 0
Item 7: Sole Dispositive Power: 3,454,456
Item 8: Shared Dispositive Power: 0
Item 9: Aggregate Amount Owned: 3,454,456
Item 10: Check Box If Aggregate Amount Excludes Certain Shares: N/A
Item 11: Percent of Class Owned: 10.4%
Item 12: Type of Reporting Person: IA

Item 1(a): Name of Issuer: Cempra Inc
Item l(b): Address of Issuer:
6340 Quadrangle Drive,Suite 100, Chapel Hill NC, 27517
Item 2(a): Name of Person Filing: Wasatch Advisors, Inc.
Item 2(b): Address: 505 Wakara Way, Salt Lake City, UT 84108
Item 2(c): Citizenship: Not Applicable
Item 2(d): Title of Class of Securities: Common Stock
Item 2(e): CUSIP Number: 15130J109
Item 3(e): Investment Adviser registered under section 203 of the Investment
Advisers Act of 1940
Item 4(a): 	Amount Owned: 3,454,456
Item 4(b): 	Percent of Class Owned: 10.4%
Item 4(c)(i): Sole Voting Power: 3,454,456
Item 4(c)(ii): Shared Voting Power: 0
Item 4(c)(iii): Sole Dispositive Power: 3,454,456
Item 4(c)(iv): Shared Dispositive Power: 0
Item 5: Check Box If Ownership Is 5% or Less of Class: [ ]
Item 6. Ownership of More Than 5% on Behalf of Another Person: N/A
Item 7: Identification of Subsidiary: Not Applicable
Item 8: Identification of Members of Group: Not Applicable
Item 9: Notice of Dissolution of Group: Not Applicable
Item 10: Certification:
By signing below I certify that, to the best of my knowledge and belief,
the securities referred to above were acquired in the ordinary course of
business and were not acquired for the purpose of and do not have the effect
of changing or influencing the control of the issuer of such securities and
were not acquired in connection with or as a participant in any transaction
having such purpose or effect.

SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete
and correct as of May 31, 2014.
Date: 06/10/14
Signature: /s/Jeff S. Cardon
Name/Title: Jeff S. Cardon/CEO
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>